Stem Cell Treatment for Osteomalacia in Delhi, India

Stem Cell Treatment for Osteomalacia in Delhi, India

Osteomalacia is a softening of bone tissue, primarily from vitamin D deficiency in adults. Osteomalacia is different from osteoporosis or osteopenia. Osteoporosis and osteopenia are conditions of weakening or complete loss of bone mass—osteomalacia is directly related to a defect in the process of making bone altogether. Osteomalacia can occur at any age, including in children (then referred to as rickets). Osteomalacic softened bones bend, bow, and in some cases fracture much easier. Therefore, osteomalacia can have a significant effect on mobility and overall health.

Hormonal regulation and mechanical forces drive alterations and remodeling of bone. Remodeling occurs at a cellular level where old bone is broken down (“resorption” or absorption) and removed with the action of osteoclasts (a type of cell). New bone is then formed. In osteomalacia the normal process of mineralizing bone is impaired. In addition, osteomalacia needs to occur due to an inadequate absorption of dietary calcium. Or the loss of phosphate through urine, which might happen through metabolic disorders such as hyperthyroidism, hypocalcemia, etc.

Symptoms might include bone pain (especially in the spine, pelvis, hips, or legs), muscle weakness, vertebral compression and/or hypocalcemia (low calcium), flattening of the pelvis, and increased incidence of fractures. The biggest issue facing an osteomalacia patient is vitamin D deficiency. Vitamin D deficiency might be caused by lack of sun exposure, poor dietary intake, or, rarely, by hereditary factors. Treatments usually include vitamin D and calcium supplementation in order to restore mineral homeostasis and remodeling processes on affected bone, which help to strengthen bone in symptomatic patients to prevent complications.

Symptoms of Osteomalacia

In the initial phase of osteomalacia, symptoms are typically absent, making clinical diagnosis difficult without diagnostic imaging such as X-rays or blood tests. Subjective musculoskeletal symptoms may already be present due to subtle defects in bone mineralization, and the patient will not realize this until later in the disorder’s progression.

As the disease progresses, typical signs and symptoms of osteomalacia will occur:

• Bone Pain: generally a dull, throbbing ache, most commonly affecting the lower back, hips, pelvis, legs, and ribs.
• Pain Worsening at Night: Discomfort usually progresses in the evening and/or with pressure applied to bones.
• Poor Relief with Rest: not to be confused with tiredness, resting does not alleviate the pain.
• Muscle Weakness: with muscle weakness, especially in the thighs and legs, completing daily activities becomes increasingly more difficult.
• Waddling Gait: With decreased muscle tone and bone weakness in the legs, walking patterns begin to change to waddling.
• Difficulty Walking: mobility can become more restrictive, with movement becoming progressively slower and tasks becoming seemingly impossible.

These highlighted symptoms indicate both impaired bone strength and weakness in muscle support to the skeleton. This makes for a situation of pain and weakness and a rotten cycle through your day’s activities. A timely diagnosis of osteomalacia and treatment with vitamin D and calcium, when indicated, is vital so that mobility does not further deteriorate or become permanent skeletal deformities.

Causes of Osteomalacia

Osteomalacia develops as a result of an impairment in the process of bone formation, where bones are not properly mineralized. For the development of strong bone, the body must have enough calcium and phosphate available to provide the mineralized structure. If these nutrients are missing from the diet or not absorbed properly, then osteomalacia can occur.

The common causes of osteomalacia include:

• Vitamin D deficiency: This is the most common cause on the planet. Because sunlight helps our skin to produce vitamin D, people who are not regularly in the sun or who do not eat a lot of vitamin D-fortified foods are at the greatest risk.
• Certain types of surgeries: Many surgical procedures involve removing part of the stomach or bypassing parts of the small intestine. These procedures can prevent the proper absorption of nutrients, allowing for deficiencies in vitamin D and calcium to occur.
• Celiac Disease: An autoimmune disorder called celiac disease occurs when people eat gluten, resulting in damage to the lining of the intestine. Damage to the intestinal lining can prevent the absorption of nutrients that cause deficiencies.
• Kidney or liver disorders: The kidneys and liver are both responsible for activating vitamin D. If there is an issue with function in either organ, the body cannot fully utilize vitamin D.
• Medications: Medications such as phenytoin (Dilantin) or phenobarbital, used for seizure control, among others, can interfere with the metabolism of vitamin D and lead to osteomalacia.

The management of osteomalacia will include repletion of vitamin D and calcium through supplementation, dietary adjustments, and correction of any underlying problems. Once properly diagnosed, accurate medical management will help patients receive evidence-based treatment, which is understood by identity through the laboratory.

Diagnosis of Osteomalacia

To diagnose a condition, a blood test will be needed by the health provider. You may have osteomalacia or another bone deficiency if you have all of these symptoms:

• Defivid D deficiency
• Calcium deficiency
• High phosphorus levels.

Your healthcare provider also can measure the alkaline phosphate isoenzymes. Increased calcium levels can suggest osteomalacia. Additional blood tests can measure the parathyroid hormone levels. High levels of the hormone indicate a vitamin D deficiency or similar issues. X-rays or other imaging scans may reveal tiny fractures of the bones. These fractures will occur in Looser’s zones of ossification. You can also fracture in the area with very minor trauma.

To make a diagnosis for osteomalacia, a bone biopsy may be needed by your caregiver. A needle will be inserted through the skin and muscle into your bone to remove a small sample. You will prepare the sample on a slide and examine it under a microscope. In most cases a diagnosis can be made with just an X-ray and blood tests without needing a bone biopsy.

Treatment of Osteomalacia

Adult stem cells stored naturally in our body tissues, including adipose tissues (fat), have greater availability from this source in volume than they do from other sources. These stem cells are all over almost every mature organ and are part of the body’s natural repair system to help to overcome the damage that occurs on a daily basis. However, when the body is not able to access enough stem cells to come close to the original repair of the area of damage, or because of aging or chronic health conditions, life events and adverse experiences cannot repair themselves and often become chronic problems in the body. Cell Cure India can extract stem cells from belly fat, concentrate them in a controlled environment, and reintroduce these stem cells into the impaired area, resulting in stimulation of natural regeneration.

Osteomalacia is caused by defective mineralization of bone and often results from a vitamin D deficiency or some related problem in absorption. Restoring levels of vitamin D and calcium through supplementation can replace what was lost, but stem cell therapy deals with damage at its cellular level and initiates an ability to improve bone formation by repairing the compromised tissue. Infused stem cells will restore the impaired area’s bone tissue and typically increase the area’s immune response to acute distress and overall protection from damage.

At Cell Cure India, patients are cared for by doctors and nurses 24/7 and stay in private VIP recovery rooms. However, to best provide the best experience and outcomes possible, patients are asked to stay at least three days for observation of their health, and hospital policies strive for continuing improvement.

FAQs

1. What is osteomalacia, and how is it different from osteoporosis?

Osteomalacia is the softening of bones, usually due to defective mineralization from vitamin D deficiency, and is not to be confused with osteoporosis. Osteoporosis is a weakness of existing bone, whereas osteomalacia causes issues with the process of making bone from the very onset.

2. How can stem cell therapy help in rectifying osteomalacia?

Stem cell therapy repairs damage at the level of cells. Adult stem cells are usually harvested from adipose (fat) tissue, concentrated, and then reinjected. This allows a patient’s impaired bone tissue to regenerate, improves bone weakness, and is, in fact, very natural bone healing.

3. What symptoms get better after stem cell therapy for osteomalacia?

The major complaints of patients include improvement in overall bone pain, muscle strength improvements, decreased risk of fractures, improved mobility, and a better quality of life over time.

4. Why stem cell treatment in Delhi, India?

Cell Cure India utilizes cutting-edge stem cell therapy, providing VIP recovery rooms, 24-hour medical supervision, and a multi-stage treatment protocol designed to protect and maximize patient safety, comfort, and effectiveness.